Product Lines

Pharmaceutical Excipients

PROSOLV® EASYtab

JRS Pharma’s "PROSOLV® EASYtab" - exciting All-in-One, High Functionality, Excipient Composite

PROSOLV® ODT

JRS Pharma to introduce its newest product derived from PROSOLV® Technology


 

ARBOCEL®

Powdered Cellulose, Ph. Eur., NF, JP
Powdered cellulose is used as an economic and inert diluent in tableting and capsule filling. Especially in wet granulation it works synergistically with other economic excipients such as starch or lactose. Combined with these, ARBOCEL® improves tablet hardness and disintegration time.

ARBOCEL® Specifications (click to open)
Grade Average Particle Size
by Laser Diffraction (µm)
Bulk Density (typical) (g/cm 3) Main Application
ARBOCEL® M80 60 0.22 Fine, fibrous grade of powdered cellulose, suitable for wet granulation.
ARBOCEL® P290 80 0.30 Fine grade with increased density and improved flow. Suitable for wet granulation and direct compression, especially in combination with MCC.
ARBOCEL® A300 250 0.35 Coarse grade with excellent flow properties used in direct compression and for capsule fillings.

CANDEX®

Candex is a soluble tablet binder that is composed mainly of dextrose with small amounts of starch oligosaccharides.

COMPACTROL®

Calcium Sulfate Dihydrate, Ph. Eur., USP/NF
COMPACTROL® is a specially processed Calcium Sulfate Dihydrate for use as a filler in tablets made by direct compression or a binder in wet granulation.

COMPACTROL® Specifications (click to open)
Grade Bulk Density Median Particle Size

COMPACTROL®

< 0.75 - 1.10 g/mL 120 µm

EMCOMPRESS®

Calcium Hydrogen Phosphate Dihydrate, Ph. Eur. Dibasic Calcium Phosphate, USP, Dihydrate
Calcium Hydrogen Phosphate Dihydrate / Dibasic Calcium Phosphate is a superior inorganic binder. It has a unique particle size, shape and density to maximize flow in high speed tablet production.

EMCOMPRESS® Specifications (click to open)
Grade Chemical Structure Main Application
EMCOMPRESS® CaHPO4 • 2 H2O Monoclinic crystal. Standard grade with excellent flow properties.
ANHYDROUS
EMCOMPRESS¨
CaHPO4 Triclinic crystal. Special grade, offers improved compressibility and moisture stability in tableting. Ideal flow enhancer for capsule fillings.

EMCOCEL®

Microcrystalline Cellulose, Ph. Eur., NF, JP

EMCOCEL® Specifications (click to open)
Grade Average Particle Size by Laser Diffraction (µm) Bulk Density
(g/cm 3)
Main Application
EMCOCEL® SP15 15 > 0.13 For use as a suspension aid and an auxiliary disintegrant.
EMCOCEL® 50M 65 0.25 - 0.37 Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.
EMCOCEL® LM50 65 0.25 - 0.37 Equal quality as grade 101/50M, but very low moisture content (< 1.5% resp. 3%) for processing water-sensitive actives.
EMCOCEL® 90M 100 0.25 - 0.37 Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.
EMCOCEL® XLM90 100 0.25 - 0.37 Equal quality to grades 102/90M, but very low moisture content (< 1.5%) for processing water-sensitive actives.
EMCOCEL® HD90 100 0.35 - 0.50 Equal quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives.
EMCOCEL¨ LP200 190 0.25 - 0.37 Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation Ð even when used with low concentrations of fine actives.

EMDEX®

Dextrates, NF
Ideal for chewable and soluble tablets, EMDEX® is the only compendial (NF) dextrate that delivers the required flow, compaction, taste masking and flavor carrying capacity. It is highly water-soluble and gives a cool smooth mouth feel.
EMDEX® is also available GMO free.

EXPLOTAB®

Sodium Starch Glycolate, Ph. Eur., NF

EXPLOTAB® Specifications (click to open)
Grade pH Value Main Application
EXPLOTAB®
5.5 - 7.5 Superdisintegrant with a rapid and high degree of swelling for capsule formulations. Especially for poor water soluble actives and tablet matrices with higher pH values.
EXPLOTAB® CLV 5.5 - 7.5 Special grade with increased number of crosslinkings.
Especially suited for wet granulation applications.

EMCOSOY®

Soy Polysaccharides
An all natural superdisintegrant, which does not contain starch or sugar.
Being a dietary fiber, it has excellent application in nutritional products.

LUBRITAB®

Hydrogenated Vegetable Oil, NF, BP
Hydrogenated Oil, JP

LUBRITAB® is made from hydrogenated cottonseed oil. As a plant-derived product it is the ideal lubricant for health supplement and neutraceutical products. It can also be used as a binder and controlled release matrix. The lubrication effect of LUBRITAB® occurs mainly at the outer parts of the tablet, which helps to overcome specific sticking and picking problems.

PROSOLV SMCC®

Silicified Microcrystalline Cellulose (Microcrystalline Cellulose, Ph. Eur., NF, JP & Silica, Colloidal Anhydrous, Ph. Eur. & Colloidal Silicon Dioxide NF & Light Anhydrous Silicic Acid JP)

High functionality excipients are inactive ingredients that meet four criteria:

  • First, they are multifunctional. They contribute two or more functions to a formulation through a single ingredient.
  • Second, they have high inherent functional performance, even at low use levels, allowing for increased batch sizes and higher drug loading.
  • Third, they require no complex processing, making them ideal for cost effective direct compression processes.
  • Lastly, they impart their high inherent functional performance to the overall formulation. This last criterion is critical since it separates high functionality excipients from other multi-functional excipients or conventional specialty grade excipients. High functionality excipients provide the means for simplifying formulation development, and improving overall operational costs while preserving the quality that is expected by the industry.

A portfolio of high functionality excipients that imparts superior flow, compaction and dispersion to a formulation. When used in direct compression, PROSOLV SMCC® can replace granulations, while significantly reducing excipient numbers and levels. PROSOLV SMCC® formulations produce distinctive, uniform, cost effective tablets.

PROSOLV SMCC® Specifications (click to open)
Grade Average Particle Size by Laser Diffraction (µm) Bulk Density
(g/cm 3)
Main Application
PROSOLV SMCC® 50 60 0.25 - 0.37 Formulas where optimal compaction is required.
PROSOLV SMCC® 90 110 0.25 - 0.37 Formulas where a balance of flow and compaction is required.*low moisture grade avaliable on request
PROSOLV
SMCC® HD90
110 0.35 - 0.50 Formulas where optimal flow and consolidation is required. *low moisture grade avaliable on request

PRUV®

Sodium Stearyl Fumarate,
Ph. Eur., NF, JPE

PRUV® is a hydrophilic lubricant. It avoids many problems associated with magnesium stearate including active incompatibility*, over lubrication, and film formation in effervescent tablets. Product development time and bioavailability of certain actives can be improved.

* e.g. Azathioprin, Cefaclor, Cilazapril, Clarithromycin, Clopidogrelacetate, Diclofenac, Fosinopril, Ibuprofen, Ketorolac, Levofloxacin, Nifedipin, Omeprazol, Ramipril, Trandolapril.

VIVAPUR®

Microcrystalline Cellulose, Ph. Eur., NF, JP

VIVAPUR® Specifications (click to open)
Grade Average Particle Size by Laser Diffraction (µm) Bulk Density
(g/cm 3)
Main Application
VIVAPUR® 101 65 0.26 - 0.31 Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.
VIVAPUR® 102 100 0.28 - 0.33 Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.
The Innovative MCC- Grade for Direct Compression
VIVAPUR® 12 180 0.30 - 0.36 Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation & even when used with low oncentrations of fine actives.
VIVAPUR® 200 250 0.31 - 0.37 Large size MCC grade with excellent flow properties for a variety of direct compression formulations.

VIVASOL®

Croscarmellose Sodium, Ph. Eur., NF, JP
VIVASOL® is a cellulose-based superdisintegrant, providing excellent results in tablet disintegration and dissolution.
Used at a level of 1 - 2% only, it is one of the most efficient superdisintegrants in the pharmaceutical market.
VIVASOL® can be used in all tableting processes. Especially good for medium soluble actives.

VIVASTAR®

Sodium Carboxymethyl Starch, JPE

VIVASTAR® Specifications (click to open)
Grade pH Value Main Application
VIVASTAR® P 5.5 - 7.5 Superdisintegrant with a rapid and high degree of swelling for capsule formulations. Especially for poor water soluble actives and tablet matrices with lower pH values.
VIVASTAR® PSF 5.5 - 7.5 Special grade with very low methanol content.
Especially suited for alcohol and moisture sensitive actives.
VIVASTAR® Low PH 3.0 - 5.0 Special grade with low pH value. Complies with Typ (B) Ph. Eur, NF.