VIVAPUR® MCC Spheres
Microcrystalline Cellulose
INTRODUCTION
VIVAPUR® MCC Spheres consist purely of microcrystalline cellulose, making them extremely robust and chemically inert. They are, therefore, excellently suited as a carrier system. API-layered VIVAPUR® MCC Spheres can be filled into capsules and compacted into tablets.
They possess a tight particle size distribution, allowing for better control and higher batch-to-batch consistency of API release profiles. The particle size uniformity minimizes segregation risks during encapsulation or tableting, permitting greater API content uniformity. Additionally, it is possible to apply different APIs in various concentrations and combine the coated spheres in a single unit dose.
VIVAPUR® MCC Spheres are available in a wide range of particle sizes.
VIVAPUR® MCC Spheres offer:
- Biologically inert
- Insoluble in water
- High degree of sphericity
- Adapted for coating and tableting
- Size < 200 µm available
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Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460 (i)
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| Grade | Size | Main Application | |
| (mesh) | (µm) | ||
| VIVAPUR® MCC Spheres 100 | 70-140 | 100-200 |
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| VIVAPUR® MCC Spheres 200 | 45-70 | 200-355 | |
| VIVAPUR® MCC Spheres 350 | 35–45 | 355–500 | |
| VIVAPUR® MCC Spheres 500 | 25–35 | 500–710 | |
| VIVAPUR® MCC Spheres 700 | 18-25 | 710-1000 | |
| VIVAPUR® MCC Spheres 1000 | 14-18 | 100-1400 | |
