Microcrystalline Cellulose

Microcrystalline Cellulose


VIVAPUR® MCC Spheres consist purely of microcrystalline cellulose, making them extremely robust and chemically inert. They are, therefore, excellently suited as a carrier system. API-layered VIVAPUR® MCC Spheres can be filled into capsules and compacted into tablets.

They possess a tight particle size distribution, allowing for better control and higher batch-to-batch consistency of API release profiles. The particle size uniformity minimizes segregation risks during encapsulation or tableting, permitting greater API content uniformity. Additionally, it is possible to apply different APIs in various concentrations and combine the coated spheres in a single unit dose.

VIVAPUR® MCC Spheres are available in a wide range of particle sizes.

VIVAPUR® MCC Spheres offer:

  • Biologically inert
  • Insoluble in water
  • High degree of sphericity
  • Adapted for coating and tableting
  • Size < 200 µm available
Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460 (i)
Grade Size Main Application
(mesh) (µm)
VIVAPUR® MCC Spheres 100 70-140 100-200
  • Water insoluble carrier
  • For organic solvent free API coating
  • Small particle sizes available
  • High robustness
VIVAPUR® MCC Spheres 200 45-70 200-355
VIVAPUR® MCC Spheres 350 35–45 355–500
VIVAPUR® MCC Spheres 500 25–35 500–710
VIVAPUR® MCC Spheres 700 18-25 710-1000
VIVAPUR® MCC Spheres 1000 14-18 100-1400

Extremely Robust and Chemically Inert

Excellently Suited as a Carrier System