VIVASOL®
Croscarmellose Sodium
INTRODUCTION
VIVASOL®, croscarmellose sodium, is a superdisintegrant specifically developed for manufacturing tablets and capsules. Its unique performance attributes have established VIVASOL® as a globally accepted product in the pharmaceutical and nutritional industries.
The fibrous nature of VIVASOL® possesses a wicking effect, which is responsible for rapid capillary transport into the tablet matrix. As a result, the VIVASOL® use level can remain low while still providing superior tablet disintegration properties.
JRS Pharma produces two croscarmellose sodium grades: VIVASOL® and VIVASOL® GF (GMO-Free). Their specifications and functional performances are similar.
VIVASOL® offers:
- Fast tablet disintegration
- Good flowability and mixing properties
- Excellent API stability
- Performs well in both direct compression and granulation processes
- Cost-effectiveness
- Guaranteed supply chain security
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Croscarmellose Sodium, Ph. Eur., NF, JP
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| Grade | Raw Material | GMO free | Loss on Drying | Solvent content | |
| VIVASOL® | cotton floc | max. 10% | max. 1% MeOH | A cellulose-based superdisintegrant, providing excellent results in tablet disintegration. Used at a level of 1 - 4 % only, it is one of the most efficient superdisintegrants in pharmaceutical technology. VIVASOL® can be used in all tableting processes. Especially good for medium soluble actives. | |
| VIVASOL® GF | wood pulp | ✓ | max. 10% | max. 0.5% EtOH | |
| VIVASOL® GF LM | wood pulp | ✓ | max. 6% | max. 0.01% EtOH | Grade with less than 6 % moisture for food applications (E468). |
| VIVASOL® SF 200 | cotton floc | max. 4% | max. 0.3% MeOH | Special grade with tighter specification for settling volume: 10 - 18 ml | |
| VIVASOL® 2HS | cotton floc | max. 10% | max. 1% MeOH | Special grade with tighter specification for settling volume: 20 - 28 ml | |
