Microcrystalline cellulose
Microcrystalline cellulose (MCC) is an odorless, tasteless, porous white powder derived from pharmaceutical grade wood pulp. With a wide range of chemical, technical, and economic benefits, MCC is one of the most widely used binder excipients for tablet formulations.
VIVAPUR® & EMCOCEL® offer:
High compactibility
Robust tablets with low friability
High production yields
Cost savings due to reduction in dosage levels
Compatibility with most APIs (inert)
GRADES - Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460(i), FCC
- VIVAPUR® 105 NV
Very fine grade, which gives a pleasant mouth feeling, masks bitter tastes and supports flavors.
VIVAPUR® 101 / EMCOCEL® 50 M
Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.
VIVAPUR® 103
Same quality as grade 101/50M, but very low moisture content (< 1.5 %) for processing water-sensitive actives.
VIVAPUR® 301
Same quality as grade 101, but increased bulk density and improved flow properties.
VIVAPUR® 102 / EMCOCEL® 90 M
Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.
VIVAPUR® 112 / EMCOCEL® XLM 90
Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives
VIVAPUR® 302 / EMCOCEL® HD 90
Same quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives.
VIVAPUR® 102 SCG / EMCOCEL® 90 M COARSE
Coarse, DC-grade MCC.
VIVAPUR® 12
Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives.
VIVAPUR® 14
Same quality to grade 12, but very low moisture content (<1.5 %) for processing water-sensitive actives.
EMCOCEL® LP 200
Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives.
VIVAPUR® 200
Large size MCC grade with excellent flow properties for a variety of direct compression formulations.
VIVAPUR® 200 XLM
Same quality to grades 200/LP200, but very low moisture content (<1.5 %) for processing water-sensitive actives.
VIVAPUR® & EMCOCEL®
Air Stream Dried Quality
Spray Dried Quality
Average Particle Size by Laser Diffraction (µm)
Bulk Density (g/mL):
VIVAPUR®
Bulk Density (g/mL):
EMCOCEL®
VIVAPUR® 105 NV
15
max 0.26
VIVAPUR® 101
EMCOCEL® 50 M
65
0.26 – 0.31
0.25 – 0.37
VIVAPUR® 103
65 0.26 – 0.31
VIVAPUR® 301
65 0.35 – 0.46
VIVAPUR® 102
EMCOCEL® 90 M
130 0.28 – 0.33
0.25 – 0.37
VIVAPUR® 112
EMCOCEL®XLM 90
130 0.30 – 0.36
0.25 – 0.37
VIVAPUR® 302
EMCOCEL® HD 90
130 0.35 – 0.50
0.38 – 0.50
VIVAPUR® 102 SCG
EMCOCEL® 90 M COARSE
170/175
0.28 – 0.34
0.25 – 0.37
VIVAPUR® 12
180
0.30 – 0.36
VIVAPUR® 14
170
0.32 – 0.40
EMCOCEL® LP 200
220
0.20 – 0.37
VIVAPUR® 200
250
0.31 – 0.37 VIVAPUR® 200 XLM
250 0.33 – 0.40