Microcrystalline cellulose
VIVAPUR® MCC Spheres consist purely of microcrystalline cellulose, making them extremely robust and chemically inert. They are, therefore, excellently suited as a carrier system. API-layered VIVAPUR® MCC Spheres can be filled into capsules and compacted into tablets.
They possess a tight particle size distribution, allowing for better control and higher batch-to-batch consistency of API release profiles. The particle size uniformity minimizes segregation risks during encapsulation or tableting, permitting greater API content uniformity. Additionally, it is possible to apply different APIs in various concentrations and combine the coated spheres in a single unit dose.
VIVAPUR® MCC Spheres are available in a wide range of particle sizes.
VIVAPUR® MCC Spheres offer:
Biologically inert
Insoluble in water
High degree of sphericity
Moisture and heat resistant
Adapted for coating and tableting
Size < 200 µm available
VIVAPUR® MCC Spheres
Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460 (i)
Grade
Size (mesh)
Size (µm)
VIVAPUR® MCC Spheres 100
70 – 140
100 – 200
VIVAPUR® MCC Spheres 200
45 – 70
200 – 355
VIVAPUR® MCC Spheres 350
35 – 45
355 – 500
VIVAPUR® MCC Spheres 500
25 – 35
500 – 710
VIVAPUR® MCC Spheres 700
18 – 25
710 – 1000
VIVAPUR® MCC Spheres 1000
14 – 18
1000 – 1400